Handbook of Tropical Medicine

expressing the respiratory activity of tissues. The final dry weight of the tissue, removed at the end of the experiment, washed, and dried, has been most widely used, and this is the only term of reference mentioned in the book. The wet weight, the initial dry weight, the total nitrogen, and the nucleic acid phosphorus of the tissues have also been put forward from time to time as terms superior to the classical basis of reference, and it would have been useful to have the benefit of the author's experience and thought on this subject. Manometric Methods is intended as a laboratory handbook, but its usefulness goes far beyond that practical goal. It is so lucid and straightforward an account of methods which are increasing tremendously in their application and interest today that every student will profit from reading it by the better understanding of how the results of work on tissues and enzymes are obtained. The book is of pocket size, is well-printed, and (an unexpected benefit of war-time paper shortages?) the paper has a matt surface much better for reading than the glossy paper of the first edition. -ALFRED E. WILHELMI.